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August 20, 2005

Umbilical Cord Stem Cells in a Microgravity Environment

An interesting merge of two technologies deomstrates great promise for the use of umbilical cord stem cells for growing tissue. Already a team of researchers have grown liver tissue and are now working to replicate pancreatic and nerve cells:

Microgravity technology developed by NASA can multiply stem cells from a newborn's blood in large enough quantities to be used to regenerate human tissue, London scientists have found.

Researchers at U.K.-based Kingston University have discovered primitive stem cells in the umbilical cord blood of infants that are similar to those from human embryos, which can be used to develop into any tissue in the body. The newly discovered human cells, called "cord-blood-derived embryonic-like stem cells" or CBEs, are more versatile than adult stem cells, found in bone marrow, which can mend damaged tissue during life.

Separating adult from CBE stem cells, the scientists can extract as many as 10,000 primitive cells from the umbilical cord blood. The scientists then use a micro-bioreactor to generate millions more, according to Dr. Colin McGuckin, director of the Stem Cell Therapy group at Kingston University.

So far, the scientists have successfully formed liver tissue from the cells, and they're now working to replicate pancreatic and nerve tissue.

[snip]

The team hopes eventually to use one unit of cord blood to replicate tissue for one patient. The bioreactors can increase the stem cell count 168-fold, McGuckin said.

Read the rest.

HT: Life at the Frontier


Posted August 20, 2005 10:00 AM


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